위암에서 새로운 TNM병기 체계에 따른 예후의 평가, 대한외과학회지, 2011. 1. Listed in SCIE

 

배정민ㆍ김세원ㆍ김상운ㆍ송선교
영남대학교 의과대학 외과학교실
대한외과학회지 2011 Jan; 80(1): 23~28
중심단어 : 위암, AJCC, 예후

Evaluation of Prognostic Values according to the New TNM Classification in Gastric Cancer
Jung Min Bae, M.D., Se Won Kim, M.D., Sang Woon Kim, M.D., Sun Kyo Song, M.D.
Department of Surgery, Yeungnam University College of Medicine, Daegu, Korea
Purpose: In 2010, the new UICC/AJCC TNM classification for gastric cancer was declared. The new classification for gastric cancer has several changes from the 6th classification. We evaluated the prognostic values and differences according to the new UICC/AJCC TNM classification. Methods: From 2000 to 2004, 1,196 patients who underwent curative resection with D1+Ղ or more lymph node dissection and with 15 or more lymph nodes retrieved were studied retrospectively. We analyzed clinical characteristics and survival outcomes retrospectively from medical records. Results: According to UICC/AJCC 7th TNM classification, the 5-year survival rate (5YSR) of each group for depth of invasion and node metastasis were significantly different. The 5YSR of stage II in 6th classification was 82.4% and the 5YSR of stage IIa and IIb in 7th classification were 92.2% and 82.9%. The 5YSR of stage IIIa and IIIb in 6th classification were 56.3% and 33.0%. The 5YSR of stage IIIa, IIIb and IIIc in 7th classification were 72.7%, 48.4% and 26.1%. In our Cox regression multivariate analysis, N stage of the 6th UICC/AJCC TNM classification was the main independent prognostic factor. Conclusion: N stage of the 6th UICC/AJCC TNM classification is a more reliable prognostic factor than N stage of the 7th UICC/AJCC TNM classification. Further study should be performed to confirm the appropriateness of N stage TNM classification for gastric cancer. (J Korean Surg Soc 2011;80:23-28)
Key_word : Gastric cancer, AJCC, Prognosis